InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HPD

Summary

InnateDB Protein

IDBP-62010.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HPD

Protein Name

4-hydroxyphenylpyruvate dioxygenase

Synonyms

4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD;

Species

Homo sapiens

Ensembl Protein

ENSP00000289004

InnateDB Gene

IDBG-62008 (HPD)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen

Biological Process

GO:0009072	aromatic amino acid family metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0000139	Golgi membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

InterPro

IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain
IPR005956 4-hydroxyphenylpyruvate dioxygenase
IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

PFAM

PF00903

PRINTS

PIRSF

PIRSF009283

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite