Homo sapiens Protein: IL1R1
Summary
InnateDB Protein IDBP-620129.1
Last Modified 2018-06-05 [Report errors or provide feedback]
Gene Symbol IL1R1
Protein Name interleukin 1 receptor type 1
Synonyms CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80;
Species Homo sapiens
Ensembl Protein ENSP00000386478
InnateDB Gene IDBG-109613 (IL1R1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 49 [view]
Protein-Protein 46 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004908 interleukin-1 receptor activity
GO:0004909 interleukin-1, Type I, activating receptor activity
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0019221 cytokine-mediated signaling pathway
GO:0070498 interleukin-1-mediated signaling pathway
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR004076 Interleukin-1 receptor type 1
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013783 Immunoglobulin-like fold
IPR015621 Interleukin-1 receptor family
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
IPR036179 Immunoglobulin-like domain superfamily
PFAM PF01582
PF13676
PF13895
PF07679
PRINTS PR01536
PR01538
PIRSF
SMART SM00255
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B8ZZ73
UniProt Splice Variant
Entrez Gene 3554
UniGene
RefSeq
HUGO HGNC:5993
OMIM 147810
CCDS
HPRD
IMGT
EMBL AC007271 KF456690
GenPept