InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mgll

Summary

InnateDB Protein

IDBP-620562.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mgll

Protein Name

monoglyceride lipase

Synonyms

AA589436; Magl; Mgl;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127374

InnateDB Gene

IDBG-167205 (Mgll)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004806	triglyceride lipase activity
GO:0008289	lipid binding
GO:0016787	hydrolase activity
GO:0042803	protein homodimerization activity
GO:0047372	acylglycerol lipase activity

Biological Process

GO:0006629	lipid metabolic process
GO:0006633	fatty acid biosynthetic process
GO:0008152	metabolic process
GO:0009966	regulation of signal transduction
GO:0019369	arachidonic acid metabolic process
GO:0019433	triglyceride catabolic process
GO:0046464	acylglycerol catabolic process
GO:0050727	regulation of inflammatory response
GO:0051930	regulation of sensory perception of pain
GO:0060292	long term synaptic depression
GO:2000124	regulation of endocannabinoid signaling pathway

Cellular Component

GO:0045202

synapse

Protein Structure and Domains

PDB ID

MGI:1346042

InterPro

IPR000073 Alpha/beta hydrolase fold-1
IPR000801 Putative esterase
IPR002921 Lipase, class 3
IPR013094 Alpha/beta hydrolase fold-3
IPR019363 Protein of unknown function DUF2305
IPR022742 Putative lysophospholipase
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00561
PF00756
PF01764
PF07859
PF10230
PF12146

PRINTS

PR00111

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite