InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Camk2d

Summary

InnateDB Protein

IDBP-620629.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Camk2d

Protein Name

calcium/calmodulin-dependent protein kinase II, delta

Synonyms

[d]-CaMKII; 2810011D23Rik; 8030469K03Rik; CaMK II;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129999

InnateDB Gene

IDBG-192589 (Camk2d)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004683	calmodulin-dependent protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0002028	regulation of sodium ion transport
GO:0006468	protein phosphorylation
GO:0006816	calcium ion transport
GO:0018105	peptidyl-serine phosphorylation
GO:0046777	protein autophosphorylation
GO:0060048	cardiac muscle contraction

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0014704	intercalated disc
GO:0030315	T-tubule
GO:0031594	neuromuscular junction
GO:0043025	neuronal cell body
GO:0043194	axon initial segment

Protein Structure and Domains

PDB ID

MGI:1341265

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF08332

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt