Version 5.4
Mus musculus Protein: S100a10
Summary
InnateDB Protein IDBP-621418.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100a10
Protein Name S100 calcium binding protein A10 (calpactin)
Synonyms 42C; AA409961; AL024248; CAL12; Cal1l; CLP11; p10; p11;
Species Mus musculus
Ensembl Protein ENSMUSP00000130712
InnateDB Gene IDBG-169560 (S100a10)
Protein Structure
UniProt Annotation
Function Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:0051099 positive regulation of binding
GO:0071229 cellular response to acid
Cellular Component
GO:0019897 extrinsic component of plasma membrane
Protein Structure and Domains
PDB ID MGI:1339468
InterPro IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF00036
PF13202
PF13405
PF01023
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08207
PhosphoSite PhosphoSite-P08207
TrEMBL Q3TC45
UniProt Splice Variant
Entrez Gene 20194
UniGene
RefSeq
MGI ID
MGI Symbol S100a10
OMIM
CCDS CCDS38526
HPRD
IMGT
EMBL AK161647 AK170919 BC025044 CH466656 M16465
GenPept AAA37363 AAH25044 BAE36511 BAE42112 EDL00658 EDL00659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca