InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Med16

Summary

InnateDB Protein

IDBP-621522.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Med16

Protein Name

mediator complex subunit 16

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128463

InnateDB Gene

IDBG-171451 (Med16)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.

Experimentally validated
Total	23 [view]
Protein-Protein	23 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	48 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0030375	thyroid hormone receptor coactivator activity
GO:0046966	thyroid hormone receptor binding

Biological Process

GO:0006366	transcription from RNA polymerase II promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0030521	androgen receptor signaling pathway
GO:0045893	positive regulation of transcription, DNA-templated
GO:2000273	positive regulation of receptor activity

Cellular Component

GO:0016592

mediator complex

Protein Structure and Domains

PDB ID

MGI:2158394

InterPro

IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
IPR021665 Mediator complex, subunit Med16

PFAM

PF00400
PF11635

PRINTS

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9QAH8

UniProt Splice Variant

Entrez Gene

216154

UniGene

Mm.260089

RefSeq

MGI ID

MGI Symbol

Med16

OMIM

CCDS

HPRD

IMGT

EMBL

AC151846

GenPept