Version 5.4
Mus musculus Gene: Med16
Summary
InnateDB Gene IDBG-171451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Med16
Gene Name mediator complex subunit 16
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000013833
Encoded Proteins
IDBP-271005
mediator complex subunit 16
IDBP-621520
mediator complex subunit 16
IDBP-621521
mediator complex subunit 16
IDBP-621522
mediator complex subunit 16
IDBP-621523
mediator complex subunit 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175221:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:79894708-79908923
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000105378 ENSMUSP00000101017
ENSMUST00000165684 ENSMUSP00000129375
ENSMUST00000170375
ENSMUST00000163125
ENSMUST00000164705 ENSMUSP00000129229
ENSMUST00000166964 ENSMUSP00000128463
ENSMUST00000170409 ENSMUSP00000126729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 48 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 48 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003712 transcription cofactor activity
GO:0003824 catalytic activity
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0030375 thyroid hormone receptor coactivator activity
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0030518 intracellular steroid hormone receptor signaling pathway
GO:0030521 androgen receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:2000273 positive regulation of receptor activity
Cellular Component
GO:0005654 nucleoplasm
GO:0016020 membrane
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000175221
View Gene Order
ENSBTAG00000047217
Not yet available
Pathways
NETPATH
REACTOME
REACT_27166
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
REACT_252217
Transcriptional regulation of white adipocyte differentiation pathway
REACT_200794
Mus musculus biological processes pathway
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257219
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_233572
Gene Expression pathway
REACT_198602
PPARA activates gene expression pathway
REACT_188576
Developmental Biology pathway
REACT_206529
Generic Transcription Pathway pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_12627
Generic Transcription Pathway pathway
REACT_27161
Transcriptional regulation of white adipocyte differentiation pathway
REACT_111045
Developmental Biology pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.260089
RefSeq NM_001163276 NM_198107 XM_006513487 XM_006513488 XM_006513489
OMIM
CCDS CCDS23996 CCDS48623
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca