InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dusp12

Summary

InnateDB Protein

IDBP-621613.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dusp12

Protein Name

dual specificity phosphatase 12

Synonyms

1190004O14Rik; AA027408; AW049275; ESTM36; LMW-DSP4; mVH1; T-DSP4; VH1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130683

InnateDB Gene

IDBG-203854 (Dusp12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity
GO:0019900	kinase binding

Biological Process

GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0033133	positive regulation of glucokinase activity

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1890614

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000340 Dual specificity phosphatase, catalytic domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR020422 Dual specificity phosphatase, subgroup, catalytic domain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF00782

PRINTS

PR00700

PIRSF

SMART

SM00194
SM00195

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PUU1

UniProt Splice Variant

Entrez Gene

80915

UniGene

RefSeq

MGI ID

MGI Symbol

Dusp12

OMIM

CCDS

HPRD

IMGT

EMBL

AC113490

GenPept