Version 5.4
| Mus musculus Gene: Dusp12 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-203854.6 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | Dusp12 | ||||||||||||||
| Gene Name | dual specificity phosphatase 12 | ||||||||||||||
| Synonyms | 1190004O14Rik; AA027408; AW049275; ESTM36; LMW-DSP4; mVH1; T-DSP4; VH1 | ||||||||||||||
| Species | Mus musculus | ||||||||||||||
| Ensembl Gene | ENSMUSG00000026659 | ||||||||||||||
| Encoded Proteins |
dual specificity phosphatase 12
dual specificity phosphatase 12
dual specificity phosphatase 12
dual specificity phosphatase 12
dual specificity phosphatase 12
dual specificity phosphatase 12
dual specificity phosphatase 12
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000081721:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 1:170873498-170885540 | ||||||||||||||
| Strand | Reverse strand | ||||||||||||||
| Band | H3 | ||||||||||||||
| Transcripts | |||||||||||||||
| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | F6ZTK6 G3UW79 | ||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 80915 | ||||||||||||||
| UniGene | |||||||||||||||
| RefSeq | NM_023173 XM_006497042 | ||||||||||||||
| OMIM | |||||||||||||||
| CCDS | CCDS15474 | ||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| MGI ID | MGI:1890614 | ||||||||||||||
| MGI Symbol | Dusp12 | ||||||||||||||
| EMBL | AC113490 CH466746 | ||||||||||||||
| GenPept | EDL03060 EDL03063 | ||||||||||||||
| RNA Seq Atlas | 80915 | ||||||||||||||