InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pik3c3

Summary

InnateDB Protein

IDBP-621657.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pik3c3

Protein Name

phosphoinositide-3-kinase, class 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128927

InnateDB Gene

IDBG-132410 (Pik3c3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005488	binding
GO:0005515	protein binding
GO:0016303	1-phosphatidylinositol-3-kinase activity

Biological Process

GO:0006468	protein phosphorylation
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
GO:0045087	innate immune response (InnateDB)
GO:0046854	phosphatidylinositol phosphorylation
GO:0048015	phosphatidylinositol-mediated signaling

Cellular Component

GO:0005942	phosphatidylinositol 3-kinase complex
GO:0045335	phagocytic vesicle

Protein Structure and Domains

PDB ID

MGI:2445019

InterPro

IPR000008 C2 domain
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR016024 Armadillo-type fold

PFAM

PF00168
PF00613
PF00792

PRINTS

PR00360

PIRSF

SMART

SM00239
SM00145
SM00142

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q824

UniProt Splice Variant

Entrez Gene

225326

UniGene

Mm.194127

RefSeq

MGI ID

MGI Symbol

Pik3c3

OMIM

CCDS

HPRD

IMGT

EMBL

AC163399

GenPept