InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: F12

Summary

InnateDB Protein

IDBP-622093.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

F12

Protein Name

coagulation factor XII (Hageman factor)

Synonyms

FXII; HAF;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125771

InnateDB Gene

IDBG-155659 (F12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0008233	peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0007596	blood coagulation
GO:0030193	regulation of blood coagulation

Cellular Component

GO:0005615

extracellular space

Protein Structure and Domains

PDB ID

MGI:1891012

InterPro

IPR001254 Peptidase S1
IPR009003 Trypsin-like cysteine/serine peptidase domain

PFAM

PF00089

PRINTS

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q698

UniProt Splice Variant

Entrez Gene

58992

UniGene

Mm.42224

RefSeq

MGI ID

MGI Symbol

F12

OMIM

CCDS

HPRD

IMGT

EMBL

CT009762

GenPept