InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cybb

Summary

InnateDB Protein

IDBP-622217.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cybb

Protein Name

cytochrome b-245, beta polypeptide

Synonyms

C88302; Cgd; CGD91-phox; Cyd; gp91-1; gp91phox; Nox2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128963

InnateDB Gene

IDBG-131158 (Cybb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0009055	electron carrier activity
GO:0016175	superoxide-generating NADPH oxidase activity
GO:0020037	heme binding
GO:0046982	protein heterodimerization activity
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0007584	response to nutrient
GO:0042493	response to drug
GO:0042554	superoxide anion generation
GO:0050665	hydrogen peroxide biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005791	rough endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0030425	dendrite
GO:0043020	NADPH oxidase complex
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:88574

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q802

UniProt Splice Variant

Entrez Gene

13058

UniGene

Mm.474696

RefSeq

MGI ID

MGI Symbol

Cybb

OMIM

CCDS

HPRD

IMGT

EMBL

AL671864

GenPept