InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Jam3

Summary

InnateDB Protein

IDBP-622371.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Jam3

Protein Name

junction adhesion molecule 3

Synonyms

1110002N23Rik; JAM-3; JAM-C; Jcam3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128003

InnateDB Gene

IDBG-145910 (Jam3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001780	neutrophil homeostasis
GO:0002250	adaptive immune response
GO:0002318	myeloid progenitor cell differentiation
GO:0002523	leukocyte migration involved in inflammatory response
GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007283	spermatogenesis
GO:0007286	spermatid development
GO:0016477	cell migration
GO:0019226	transmission of nerve impulse
GO:0030010	establishment of cell polarity
GO:0042552	myelination
GO:0045087	innate immune response (InnateDB)
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion

Cellular Component

GO:0005911	cell-cell junction
GO:0005923	tight junction
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0033010	paranodal junction
GO:0043220	Schmidt-Lanterman incisure

Protein Structure and Domains

PDB ID

MGI:1933825

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF07679
PF07686
PF00047
PF08205

PRINTS

PIRSF

SMART

SM00406
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite