InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccr5

Summary

InnateDB Protein

IDBP-622429.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccr5

Protein Name

chemokine (C-C motif) receptor 5

Synonyms

AM4-7; CD195; Cmkbr5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127328

InnateDB Gene

IDBG-258112 (Ccr5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0016493	C-C chemokine receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0006952	defense response
GO:0007186	G-protein coupled receptor signaling pathway
GO:0070098	chemokine-mediated signaling pathway

Cellular Component

GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:107182

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000355 Chemokine receptor family
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR00657

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9Q3E5

UniProt Splice Variant

Entrez Gene

12774

UniGene

Mm.431882

RefSeq

MGI ID

MGI Symbol

Ccr5

OMIM

CCDS

HPRD

IMGT

EMBL

AC168021

GenPept