InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: B3GNT4

Summary

InnateDB Protein

IDBP-62256.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

B3GNT4

Protein Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000319636

InnateDB Gene

IDBG-62254 (B3GNT4)

Protein Structure

UniProt Annotation

Function

Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Mainly expressed in brain tissues such as whole brain, hippocampus, amygdala, cerebellum and caudate nucleus. Also expressed in colon, esophagus and kidney. {ECO:0000269PubMed:11042166}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008378	galactosyltransferase activity
GO:0016757	transferase activity, transferring glycosyl groups

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006486	protein glycosylation
GO:0016266	O-glycan processing
GO:0018146	keratan sulfate biosynthetic process
GO:0030203	glycosaminoglycan metabolic process
GO:0042339	keratan sulfate metabolic process
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process
GO:0044281	small molecule metabolic process