InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myo18a

Summary

InnateDB Protein

IDBP-622640.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myo18a

Protein Name

myosin XVIIIA

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130696

InnateDB Gene

IDBG-201810 (Myo18a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0043531	ADP binding
GO:0044822	poly(A) RNA binding
GO:0051015	actin filament binding

Biological Process

GO:0007030	Golgi organization
GO:0008152	metabolic process
GO:0016477	cell migration
GO:0031032	actomyosin structure organization
GO:0048194	Golgi vesicle budding
GO:0050714	positive regulation of protein secretion

Cellular Component

GO:0000139	Golgi membrane
GO:0005802	trans-Golgi network
GO:0005856	cytoskeleton
GO:0016020	membrane
GO:0016459	myosin complex
GO:0042641	actomyosin

Protein Structure and Domains

PDB ID

MGI:2667185

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001478 PDZ domain
IPR001609 Myosin head, motor domain
IPR002928 Myosin tail
IPR009053 Prefoldin
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00595
PF13180
PF00063
PF01576

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00228
SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt