Version 5.4
Mus musculus Protein: Calm3
Summary
InnateDB Protein IDBP-622747.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Calm3
Protein Name calmodulin 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000133559
InnateDB Gene IDBG-147270 (Calm3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 70 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 70 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008179 adenylate cyclase binding
GO:0019904 protein domain specific binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0031432 titin binding
GO:0031800 type 3 metabotropic glutamate receptor binding
GO:0031996 thioesterase binding
GO:0031997 N-terminal myristoylation domain binding
GO:0043274 phospholipase binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0044325 ion channel binding
GO:0048306 calcium-dependent protein binding
GO:0050998 nitric-oxide synthase binding
GO:0072542 protein phosphatase activator activity
Biological Process
GO:0001975 response to amphetamine
GO:0002027 regulation of heart rate
GO:0005513 detection of calcium ion
GO:0007190 activation of adenylate cyclase activity
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0019722 calcium-mediated signaling
GO:0032465 regulation of cytokinesis
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0035307 positive regulation of protein dephosphorylation
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051412 response to corticosterone
GO:0055117 regulation of cardiac muscle contraction
GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity
GO:1901841 regulation of high voltage-gated calcium channel activity
Cellular Component
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005876 spindle microtubule
GO:0005886 plasma membrane
GO:0030017 sarcomere
GO:0030426 growth cone
GO:0034704 calcium channel complex
Protein Structure and Domains
PDB ID MGI:103249
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UX57
UniProt Splice Variant
Entrez Gene 12315
UniGene Mm.414403
RefSeq
MGI ID
MGI Symbol Calm3
OMIM
CCDS
HPRD
IMGT
EMBL AC165955
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca