InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pitx1

Summary

InnateDB Protein

IDBP-622810.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pitx1

Protein Name

paired-like homeodomain transcription factor 1

Synonyms

Bft; P-OTX; Potx; Ptx1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000134609

InnateDB Gene

IDBG-156932 (Pitx1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001190	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001501	skeletal system development
GO:0006355	regulation of transcription, DNA-templated
GO:0014707	branchiomeric skeletal muscle development
GO:0021983	pituitary gland development
GO:0035116	embryonic hindlimb morphogenesis
GO:0035137	hindlimb morphogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048625	myoblast fate commitment
GO:0051216	cartilage development

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005730	nucleolus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:107374

InterPro

IPR001356 Homeobox domain
IPR009057 Homeodomain-like

PFAM

PF00046

PRINTS

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UZS0

UniProt Splice Variant

Entrez Gene

18740

UniGene

Mm.135195

RefSeq

MGI ID

MGI Symbol

Pitx1

OMIM

CCDS

HPRD

IMGT

EMBL

AC129780

GenPept