Version 5.4
Mus musculus Protein: A4galt
Summary
InnateDB Protein IDBP-623357.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol A4galt
Protein Name alpha 1,4-galactosyltransferase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000129719
InnateDB Gene IDBG-168008 (A4galt)
Protein Structure
UniProt Annotation
Function Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins (By similarity). {ECO:0000250UniProtKB:Q9NPC4}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0015643 toxic substance binding
GO:0050512 lactosylceramide 4-alpha-galactosyltransferase activity
Biological Process
GO:0001576 globoside biosynthetic process
GO:0006486 protein glycosylation
GO:0007009 plasma membrane organization
Cellular Component
GO:0000139 Golgi membrane
GO:0005795 Golgi stack
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:3512453
InterPro IPR007577 Glycosyltransferase, DXD sugar-binding motif
IPR007652 Alpha 1,4-glycosyltransferase domain
PFAM PF04488
PF04572
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q67BJ4
PhosphoSite PhosphoSite-Q67BJ4
TrEMBL Q3UF00
UniProt Splice Variant
Entrez Gene 239559
UniGene Mm.323805
RefSeq NP_001164425
MGI ID
MGI Symbol A4galt
OMIM
CCDS CCDS27699
HPRD
IMGT
EMBL AK149186 AY371179 BC138844 BC138845 CH466550 DQ143885
GenPept AAI38845 AAI38846 AAR18365 ABA25853 BAE28761 EDL04477

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca