InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igfbp7

Summary

InnateDB Protein

IDBP-623513.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igfbp7

Protein Name

insulin-like growth factor binding protein 7

Synonyms

AGM; Fstl2; Mac25;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128318

InnateDB Gene

IDBG-174285 (Igfbp7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005520	insulin-like growth factor binding

Biological Process

GO:0001558	regulation of cell growth
GO:0007155	cell adhesion
GO:0007566	embryo implantation
GO:0009408	response to heat
GO:0014070	response to organic cyclic compound
GO:0032526	response to retinoic acid
GO:0032870	cellular response to hormone stimulus
GO:0048839	inner ear development
GO:0050810	regulation of steroid biosynthetic process
GO:0051414	response to cortisol

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1352480

InterPro

IPR000867 Insulin-like growth factor-binding protein, IGFBP
IPR002350 Kazal domain
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR011390 Insulin-like growth factor binding protein-related protein (IGFBP-rP), MAC25
IPR013098 Immunoglobulin I-set

PFAM

PF00219
PF00050
PF07648
PF07679

PRINTS

PIRSF

PIRSF018239

SMART

SM00121
SM00280
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt