Mus musculus Protein: Hmgcr
Summary
InnateDB Protein IDBP-623972.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hmgcr
Protein Name 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms HMG-CoAR; Red;
Species Mus musculus
Ensembl Protein ENSMUSP00000128642
InnateDB Gene IDBG-174808 (Hmgcr)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662 coenzyme binding
Biological Process
GO:0015936 coenzyme A metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID MGI:96159
InterPro IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II
IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding
IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding
PFAM PF00368
PRINTS PR00071
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 15357
UniGene Mm.489666
RefSeq
MGI ID
MGI Symbol Hmgcr
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept