Version 5.4
Mus musculus Protein: Ccne2
Summary
InnateDB Protein IDBP-624071.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccne2
Protein Name cyclin E2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000130693
InnateDB Gene IDBG-129263 (Ccne2)
Protein Structure
UniProt Annotation
Function Essential for the control of the cell cycle at the late G1 and early S phase.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Highest levels in adult testis, thymus and brain. Lower levels in placenta, spleen and colon.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006270 DNA replication initiation
GO:0051301 cell division
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1329034
InterPro IPR004367 Cyclin, C-terminal domain
IPR006671 Cyclin, N-terminal
IPR013763 Cyclin-like
IPR014400 Cyclin A/B/D/E/F
PFAM PF02984
PF00134
PRINTS
PIRSF PIRSF001771
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z238
PhosphoSite PhosphoSite-Q9Z238
TrEMBL Q544H6
UniProt Splice Variant
Entrez Gene 12448
UniGene Mm.35867
RefSeq NP_001032211
MGI ID
MGI Symbol Ccne2
OMIM
CCDS CCDS17965
HPRD
IMGT
EMBL AF091432 AF106691 AK037791 AK158720 AK167428 CH466538
GenPept AAC80527 AAD08817 BAC29873 BAE34625 BAE39516 EDL05656

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca