Version 5.4
Mus musculus Protein: Taf5l
Summary
InnateDB Protein IDBP-624253.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Taf5l
Protein Name TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
Synonyms 1110005N04Rik; AI849020;
Species Mus musculus
Ensembl Protein ENSMUSP00000128710
InnateDB Gene IDBG-199943 (Taf5l)
Protein Structure
UniProt Annotation
Function Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0043966 histone H3 acetylation
Cellular Component
GO:0005634 nucleus
GO:0030914 STAGA complex
GO:0033276 transcription factor TFTC complex
Protein Structure and Domains
PDB ID MGI:1919039
InterPro IPR001680 WD40 repeat
IPR007582 TFIID subunit, WD40-associated region
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF04494
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91WQ5
PhosphoSite PhosphoSite-Q91WQ5
TrEMBL Q3U3C7
UniProt Splice Variant
Entrez Gene 102162
UniGene Mm.490582
RefSeq NP_598727
MGI ID
MGI Symbol Taf5l
OMIM
CCDS CCDS22767
HPRD
IMGT
EMBL AK033477 AK089463 AK154832 BC013550
GenPept AAH13550 BAC28309 BAC40894 BAE32861

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca