Version 5.4
Mus musculus Protein: Icmt
Summary
InnateDB Protein IDBP-624444.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Icmt
Protein Name isoprenylcysteine carboxyl methyltransferase
Synonyms 1700008E11Rik; C80758; Gm13095; HSTE14; OTTMUSG00000010406; pcCMT; PPMT; STE14;
Species Mus musculus
Ensembl Protein ENSMUSP00000133950
InnateDB Gene IDBG-206599 (Icmt)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0008140 cAMP response element binding protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0006479 protein methylation
GO:0006481 C-terminal protein methylation
GO:0008104 protein localization
GO:0008284 positive regulation of cell proliferation
GO:0035264 multicellular organism growth
GO:0046578 regulation of Ras protein signal transduction
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID MGI:1888594
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6PGA6
UniProt Splice Variant
Entrez Gene 57295
UniGene Mm.475570
RefSeq
MGI ID
MGI Symbol Icmt
OMIM
CCDS
HPRD
IMGT
EMBL AL611985 BC057132
GenPept AAH57132

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca