Version 5.4
| Mus musculus Protein: Itih1 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-624450.2 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Itih1 | ||||||
| Protein Name | inter-alpha trypsin inhibitor, heavy chain 1 | ||||||
| Synonyms | Intin1; Itih-1; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000126449 | ||||||
| InnateDB Gene | IDBG-143929 (Itih1) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. {ECO:0000250}. | ||||||
| Subcellular Localization | Secreted. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Liver specific. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:96618 | ||||||
| InterPro |
IPR002035
von Willebrand factor, type A IPR010600 Inter-alpha-trypsin inhibitor heavy chain, C-terminal IPR013694 VIT domain IPR027396 DsrEFH-like |
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| PFAM |
PF00092
PF06668 PF08487 PF13757 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00327
SM00609 |
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q61702 | ||||||
| PhosphoSite | PhosphoSite- | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 16424 | ||||||
| UniGene | Mm.3227 | ||||||
| RefSeq | NP_032432 | ||||||
| MGI ID | |||||||
| MGI Symbol | Itih1 | ||||||
| OMIM | |||||||
| CCDS | CCDS49435 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK149500 CH466573 X70391 | ||||||
| GenPept | BAE28922 CAA49841 EDL24774 | ||||||