Version 5.4
Mus musculus Gene: Itih1
Summary
InnateDB Gene IDBG-143929.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Itih1
Gene Name inter-alpha trypsin inhibitor, heavy chain 1
Synonyms Intin1; Itih-1
Species Mus musculus
Ensembl Gene ENSMUSG00000006529
Encoded Proteins
IDBP-143931
inter-alpha trypsin inhibitor, heavy chain 1
IDBP-624450
inter-alpha trypsin inhibitor, heavy chain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000055957:
The protein encoded by this gene is the heavy chain of a serine protease inhibitor that may serve to carry hyaluronan in plasma. This gene is part of a cluster of similar genes on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:30929180-30943289
Strand Reverse strand
Band B
Transcripts
ENSMUST00000006704 ENSMUSP00000006704
ENSMUST00000163118 ENSMUSP00000126449
ENSMUST00000166913
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030212 hyaluronan metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000055957
View Gene Order
ENSBTAG00000007843
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.3227
RefSeq NM_008406 XM_006518583 XM_006518584
OMIM
CCDS CCDS49435
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca