Version 5.4
Mus musculus Protein: Sfpi1
Summary
InnateDB Protein IDBP-624592.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sfpi1
Protein Name SFFV proviral integration 1
Synonyms Dis-1; Dis1; PU.1; Sfpi-1; Sfpi1; Spi-1; Tcfpu1; Tfpu.1;
Species Mus musculus
Ensembl Protein ENSMUSP00000130368
InnateDB Gene IDBG-190185 (Sfpi1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 100 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.
Experimentally validated
Total 100 [view]
Protein-Protein 46 [view]
Protein-DNA 53 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 63 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001944 vasculature development
GO:0002320 lymphoid progenitor cell differentiation
GO:0002573 myeloid leukocyte differentiation
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0030098 lymphocyte differentiation
GO:0030218 erythrocyte differentiation
GO:0030225 macrophage differentiation
GO:0030851 granulocyte differentiation
GO:0035019 somatic stem cell maintenance
GO:0043011 myeloid dendritic cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060033 anatomical structure regression
GO:1902262 apoptotic process involved in patterning of blood vessels
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:98282
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q6W1
UniProt Splice Variant
Entrez Gene 20375
UniGene Mm.484371
RefSeq
MGI ID
MGI Symbol Spi1
OMIM
CCDS
HPRD
IMGT
EMBL AL691450
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca