InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kcne1l

Summary

InnateDB Protein

IDBP-624699.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kcne1l

Protein Name

potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene

Synonyms

1500015C14Rik; Kcne5; Mink;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127773

InnateDB Gene

IDBG-486772 (Kcne1l)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Detected in embryonal dorsal root and nerve ganglia, in the somites and in myoepicardial layer of the developing heart wall. Detected at lower levels in the central nervous system (CNS) and in developing limb.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005249	voltage-gated potassium channel activity
GO:0015459	potassium channel regulator activity
GO:0044325	ion channel binding
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization

Biological Process

GO:0006811	ion transport
GO:0008016	regulation of heart contraction
GO:0060048	cardiac muscle contraction
GO:0060306	regulation of membrane repolarization
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
GO:0071435	potassium ion export
GO:0071805	potassium ion transmembrane transport
GO:0086005	ventricular cardiac muscle cell action potential
GO:0086013	membrane repolarization during cardiac muscle cell action potential
GO:0086014	atrial cardiac muscle cell action potential
GO:0086091	regulation of heart rate by cardiac conduction
GO:1901379	regulation of potassium ion transmembrane transport
GO:1901380	negative regulation of potassium ion transmembrane transport
GO:1901381	positive regulation of potassium ion transmembrane transport
GO:2001257	regulation of cation channel activity