Version 5.4
Mus musculus Protein: Oas3
Summary
InnateDB Protein IDBP-624893.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Oas3
Protein Name 2'-5' oligoadenylate synthetase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000125873
InnateDB Gene IDBG-196327 (Oas3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001730 2'-5'-oligoadenylate synthetase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
Biological Process
GO:0006955 immune response
GO:0008152 metabolic process
GO:0045087 innate immune response (InnateDB)
GO:0051607 defense response to virus
Cellular Component
Protein Structure and Domains
PDB ID MGI:2180850
InterPro IPR018952 2\'-5\'-oligoadenylate synthetase 1, domain 2/C-terminal
PFAM PF10421
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F7CXR7
UniProt Splice Variant
Entrez Gene 246727
UniGene Mm.204887
RefSeq
MGI ID
MGI Symbol Oas3
OMIM
CCDS
HPRD
IMGT
EMBL AC115937
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca