Mus musculus Protein: Irf5
Summary
InnateDB Protein IDBP-624912.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Irf5
Protein Name interferon regulatory factor 5
Synonyms AW491843; mirf5;
Species Mus musculus
Ensembl Protein ENSMUSP00000130548
InnateDB Gene IDBG-132026 (Irf5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 9 [view]
Protein-DNA 10 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 52 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000975 regulatory region DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0032494 response to peptidoglycan
GO:0032495 response to muramyl dipeptide
GO:0043065 positive regulation of apoptotic process
GO:0045087 innate immune response (InnateDB)
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1350924
InterPro IPR001346 Interferon regulatory factor DNA-binding domain
PFAM PF00605
PRINTS PR00267
PIRSF
SMART SM00348
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q5T2
UniProt Splice Variant
Entrez Gene 27056
UniGene Mm.6479
RefSeq
MGI ID
MGI Symbol Irf5
OMIM
CCDS
HPRD
IMGT
EMBL AC079276
GenPept