Version 5.4
Mus musculus Protein: Itga8
Summary
InnateDB Protein IDBP-624996.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Itga8
Protein Name integrin alpha 8
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000134154
InnateDB Gene IDBG-137042 (Itga8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001656 metanephros development
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007613 memory
GO:0030030 cell projection organization
GO:0030198 extracellular matrix organization
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0042472 inner ear morphogenesis
Cellular Component
GO:0008305 integrin complex
GO:0045177 apical part of cell
Protein Structure and Domains
PDB ID MGI:109442
InterPro IPR000413 Integrin alpha chain
IPR013517 FG-GAP repeat
IPR013519 Integrin alpha beta-propellor
IPR013649 Integrin alpha-2
PFAM PF01839
PF14312
PF08441
PRINTS PR01185
PIRSF
SMART SM00191
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UYN5
UniProt Splice Variant
Entrez Gene 241226
UniGene Mm.329997
RefSeq
MGI ID
MGI Symbol Itga8
OMIM
CCDS
HPRD
IMGT
EMBL AL845313
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca