InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Opn4

Summary

InnateDB Protein

IDBP-625026.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Opn4

Protein Name

opsin 4 (melanopsin)

Synonyms

1110007J02Rik; Gm533;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126136

InnateDB Gene

IDBG-150388 (Opn4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005502	11-cis retinal binding
GO:0008020	G-protein coupled photoreceptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0016056	rhodopsin mediated signaling pathway
GO:0018298	protein-chromophore linkage
GO:0042752	regulation of circadian rhythm
GO:0048511	rhythmic process

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1353425

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001760 Opsin
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019426 7TM GPCR, serpentine receptor class v (Srv)
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10323
PF10328

PRINTS

PR00237
PR00238

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9QXZ9