InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sin3a

Summary

InnateDB Protein

IDBP-625734.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sin3a

Protein Name

transcriptional regulator, SIN3A (yeast)

Synonyms

AW553200; mKIAA4126; mSin3A; Sin3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126718

InnateDB Gene

IDBG-169269 (Sin3a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 89 experimentally validated interaction(s) in this database.
They are also associated with 166 interaction(s) predicted by orthology.

Experimentally validated
Total	89 [view]
Protein-Protein	83 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	4 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	166 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001103	RNA polymerase II repressing transcription factor binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0002244	hematopoietic progenitor cell differentiation
GO:0006260	DNA replication
GO:0006355	regulation of transcription, DNA-templated
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
GO:0034613	cellular protein localization
GO:0043066	negative regulation of apoptotic process
GO:0051595	response to methylglyoxal
GO:0071333	cellular response to glucose stimulus

Cellular Component

GO:0000776	kinetochore
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0017053	transcriptional repressor complex

Protein Structure and Domains

PDB ID

MGI:107157

InterPro

IPR003822 Paired amphipathic helix

PFAM

PF02671

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PXF9

UniProt Splice Variant

Entrez Gene

20466

UniGene

Mm.15755

RefSeq

MGI ID

MGI Symbol

Sin3a

OMIM

CCDS

HPRD

IMGT

EMBL

AC132406

GenPept