InnateDB Protein
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IDBP-625876.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Jmjd1c
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Protein Name
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jumonji domain containing 1C
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Synonyms
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5430433L24Rik; D630035I23Rik; Jmjdic; TRIP8;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000133700
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InnateDB Gene
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IDBG-159742 (Jmjd1c)
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Protein Structure
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Function |
Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
9 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1918614
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InterPro |
IPR003347
JmjC domain
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PFAM |
PF02373
PF08007
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PRINTS |
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PIRSF |
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SMART |
SM00558
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TIGRFAMs |
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Modification |
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SwissProt |
Q69ZK6
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PhosphoSite |
PhosphoSite-Q69ZK6
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TrEMBL |
G3UYW3
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UniProt Splice Variant |
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Entrez Gene |
108829
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UniGene |
Mm.484351
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RefSeq |
NP_001229325
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MGI ID |
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MGI Symbol |
Jmjd1c
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OMIM |
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CCDS |
CCDS56708
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HPRD |
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IMGT |
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EMBL |
AC155712
AC156272
AK077400
AK082106
AK085500
AK173162
BC068318
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GenPept |
AAH68318
BAC36783
BAC38410
BAC39458
BAD32440
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