Version 5.4
Homo sapiens Protein: NADSYN1
Summary
InnateDB Protein IDBP-62593.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NADSYN1
Protein Name NAD synthetase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000326424
InnateDB Gene IDBG-62591 (NADSYN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Biological Process
GO:0006766 vitamin metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0009435 NAD biosynthetic process
GO:0019674 NAD metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR003010 Carbon-nitrogen hydrolase
IPR003694 NAD(+) synthetase
IPR014445 Glutamine-dependent NAD(+) synthetase
IPR022310 NAD/GMP synthase
PFAM PF00795
PF02540
PRINTS
PIRSF PIRSF006630
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6IA69
PhosphoSite PhosphoSite-Q6IA69
TrEMBL E9PNF5
UniProt Splice Variant
Entrez Gene 55191
UniGene Hs.738814
RefSeq NP_060631
HUGO HGNC:29832
OMIM 608285
CCDS CCDS8201
HPRD 16309
IMGT
EMBL AB091316 AK001493 AK022436 AP000867 AP002387 BC003638 BC003666 CR457286
GenPept AAH03638 AAH03666 BAA91722 BAB14034 BAC65148 CAG33567

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca