InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pax7

Summary

InnateDB Protein

IDBP-626061.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pax7

Protein Name

paired box gene 7

Synonyms

Pax-7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133536

InnateDB Gene

IDBG-201015 (Pax7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000983	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006338	chromatin remodeling
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007519	skeletal muscle tissue development
GO:0009887	organ morphogenesis
GO:0010453	regulation of cell fate commitment
GO:0010468	regulation of gene expression
GO:0014813	satellite cell commitment
GO:0021527	spinal cord association neuron differentiation
GO:0021904	dorsal/ventral neural tube patterning
GO:0031062	positive regulation of histone methylation
GO:0043393	regulation of protein binding
GO:0043403	skeletal muscle tissue regeneration
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048663	neuron fate commitment
GO:0048706	embryonic skeletal system development
GO:0051216	cartilage development
GO:0060415	muscle tissue morphogenesis
GO:2000288	positive regulation of myoblast proliferation

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

MGI:97491

InterPro

IPR001356 Homeobox domain
IPR001523 Paired domain
IPR009057 Homeodomain-like
IPR022106 Paired box protein 7

PFAM

PF00046
PF00292
PF12360

PRINTS

PR00027

PIRSF

SMART

SM00389
SM00351

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q7TPG3

UniProt Splice Variant

Entrez Gene

18509

UniGene

Mm.445608

RefSeq

MGI ID

MGI Symbol

Pax7

OMIM

CCDS

HPRD

IMGT

EMBL

AL831790 AL844480 AY328081

GenPept

AAP92423