InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lrp1b

Summary

InnateDB Protein

IDBP-626118.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lrp1b

Protein Name

low density lipoprotein-related protein 1B (deleted in tumors)

Synonyms

9630004P12Rik; LRP-DIT;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129192

InnateDB Gene

IDBG-167476 (Lrp1b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005041	low-density lipoprotein receptor activity
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0006898

receptor-mediated endocytosis

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:2151136

InterPro

IPR000033 LDLR class B repeat
IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal

PFAM

PF00058
PF00008
PF07645
PF00057

PRINTS

PR00261

PIRSF

SMART

SM00135
SM00181
SM00179
SM00192

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt