Version 5.4
Mus musculus Gene: Lrp1b
Summary
InnateDB Gene IDBG-167476.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lrp1b
Gene Name low density lipoprotein-related protein 1B (deleted in tumors)
Synonyms 9630004P12Rik; LRP-DIT
Species Mus musculus
Ensembl Gene ENSMUSG00000049252
Encoded Proteins
IDBP-167480
low density lipoprotein-related protein 1B (deleted in tumors)
IDBP-539991
low density lipoprotein-related protein 1B (deleted in tumors)
IDBP-626118
low density lipoprotein-related protein 1B (deleted in tumors)
IDBP-789880
low density lipoprotein-related protein 1B (deleted in tumors)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168702:
LRP1B belongs to the low density lipoprotein (LDL) receptor gene family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands (Liu et al., 2001 [PubMed 11384978]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:40595248-42653598
Strand Reverse strand
Band B
Transcripts
ENSMUST00000052550 ENSMUSP00000054275
ENSMUST00000142546 ENSMUSP00000117212
ENSMUST00000129974
ENSMUST00000134032
ENSMUST00000138700
ENSMUST00000133104
ENSMUST00000142688
ENSMUST00000167270 ENSMUSP00000129192
ENSMUST00000185258 ENSMUSP00000139874
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005041 low-density lipoprotein receptor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000168702
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.441398 Mm.448687
RefSeq NM_053011
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca