InnateDB Protein
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IDBP-626225.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Nlrx1
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Protein Name
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NLR family member X1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000127531
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InnateDB Gene
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IDBG-156238 (Nlrx1)
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Protein Structure
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Function |
Participates in antiviral signaling. {ECO:0000250}.
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Subcellular Localization |
Mitochondrion outer membrane {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
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Biological Process |
GO:0016032
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viral process
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GO:0032688
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negative regulation of interferon-beta production
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GO:0032715
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negative regulation of interleukin-6 production
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GO:0039536
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negative regulation of RIG-I signaling pathway
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GO:0043124
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negative regulation of I-kappaB kinase/NF-kappaB signaling
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GO:0045087
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innate immune response (InnateDB)
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GO:0045824
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negative regulation of innate immune response
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GO:0050728
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negative regulation of inflammatory response
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Cellular Component |
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PDB ID |
MGI:2429611
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InterPro |
IPR003590
Leucine-rich repeat, ribonuclease inhibitor subtype
IPR007111
NACHT nucleoside triphosphatase
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
SM00368
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TIGRFAMs |
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Modification |
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SwissProt |
Q3TL44
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
270151
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UniGene |
Mm.466338
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RefSeq |
NP_001157214
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MGI ID |
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MGI Symbol |
Nlrx1
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OMIM |
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CCDS |
CCDS23100
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HPRD |
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IMGT |
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EMBL |
AK089260
AK145988
AK166689
BC050054
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GenPept |
AAH50054
BAC40818
BAE26810
BAE38948
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