InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Guk1

Summary

InnateDB Protein

IDBP-626263.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Guk1

Protein Name

guanylate kinase 1

Synonyms

AA409738; AL033299; AL033300; AV026611; Gmk; Guk-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000134236

InnateDB Gene

IDBG-178338 (Guk1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004385	guanylate kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0016301	kinase activity

Biological Process

GO:0006185	dGDP biosynthetic process
GO:0019673	GDP-mannose metabolic process
GO:0034436	glycoprotein transport
GO:0046034	ATP metabolic process
GO:0046037	GMP metabolic process
GO:0046054	dGMP metabolic process
GO:0046060	dATP metabolic process
GO:0046711	GDP biosynthetic process
GO:0046939	nucleotide phosphorylation

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

MGI:95871

InterPro

IPR004881 Ribosome biogenesis GTPase RsgA, putative
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR010488 Zeta toxin domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF03193
PF00625
PF06414

PRINTS

PIRSF

SMART

SM00072

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UYV3

UniProt Splice Variant

Entrez Gene

14923

UniGene

RefSeq

MGI ID

MGI Symbol

Guk1

OMIM

CCDS

HPRD

IMGT

EMBL

AL645854

GenPept