InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arid3b

Summary

InnateDB Protein

IDBP-626346.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arid3b

Protein Name

AT rich interactive domain 3B (BRIGHT-like)

Synonyms

Bdp; Dri2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130173

InnateDB Gene

IDBG-170953 (Arid3b)

Protein Structure

UniProt Annotation

Function

Transcription factor involved in the production of cranial mesenchymal tissues. Favors nuclear targeting of ARID3A. {ECO:0000269PubMed:16530748}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00355}.

Disease Associations

Tissue Specificity

Expressed at high levels in testis. Also expressed in prostate, thyroid and thymus. {ECO:0000269PubMed:16530748}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0007275	multicellular organismal development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter