InnateDB Protein
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IDBP-626354.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Arid3b
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Protein Name
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AT rich interactive domain 3B (BRIGHT-like)
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Synonyms
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Bdp; Dri2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000131677
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InnateDB Gene
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IDBG-170953 (Arid3b)
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Protein Structure
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Function |
Transcription factor involved in the production of cranial mesenchymal tissues. Favors nuclear targeting of ARID3A. {ECO:0000269PubMed:16530748}.
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Subcellular Localization |
Nucleus {ECO:0000255PROSITE- ProRule:PRU00355}.
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Disease Associations |
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Tissue Specificity |
Expressed at high levels in testis. Also expressed in prostate, thyroid and thymus. {ECO:0000269PubMed:16530748}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
9 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000978
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RNA polymerase II core promoter proximal region sequence-specific DNA binding
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GO:0000980
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RNA polymerase II distal enhancer sequence-specific DNA binding
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GO:0001077
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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0001205
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RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0003677
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DNA binding
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Biological Process |
GO:0006351
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transcription, DNA-templated
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GO:0007275
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multicellular organismal development
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:1930768
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InterPro |
IPR001606
ARID/BRIGHT DNA-binding domain
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PFAM |
PF01388
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PRINTS |
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PIRSF |
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SMART |
SM00501
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z1N7
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PhosphoSite |
PhosphoSite-Q9Z1N7
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
56380
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UniGene |
Mm.425588
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RefSeq |
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MGI ID |
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MGI Symbol |
Arid3b
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AF116847
AK139455
BC049776
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GenPept |
AAD09134
AAH49776
BAE24019
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