InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myh2

Summary

InnateDB Protein

IDBP-626400.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myh2

Protein Name

myosin, heavy polypeptide 2, skeletal muscle, adult

Synonyms

MHC2A; Myh2a; MyHC-IIa; Myhs-f; Myhs-f1; Myhsf1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129544

InnateDB Gene

IDBG-187156 (Myh2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0001778	plasma membrane repair
GO:0006412	translation
GO:0008152	metabolic process
GO:0014823	response to activity
GO:0016192	vesicle-mediated transport
GO:0070252	actin-mediated cell contraction

Cellular Component

GO:0005622	intracellular
GO:0005730	nucleolus
GO:0005794	Golgi apparatus
GO:0005826	actomyosin contractile ring
GO:0005840	ribosome
GO:0005859	muscle myosin complex
GO:0005911	cell-cell junction
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0016459	myosin complex
GO:0030016	myofibril
GO:0031672	A band
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

MGI:1339710

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR001854 Ribosomal protein L29
IPR002928 Myosin tail
IPR004009 Myosin, N-terminal, SH3-like
IPR009053 Prefoldin
IPR010989 t-SNARE
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00063
PF00831
PF01576
PF02736

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt