InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SSR3

Summary

InnateDB Protein

IDBP-62667.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SSR3

Protein Name

signal sequence receptor, gamma (translocon-associated protein gamma)

Synonyms

TRAPG;

Species

Homo sapiens

Ensembl Protein

ENSP00000265044

InnateDB Gene

IDBG-62665 (SSR3)

Protein Structure

UniProt Annotation

Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Subcellular Localization

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.

Experimentally validated
Total	22 [view]
Protein-Protein	20 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006412	translation
GO:0006613	cotranslational protein targeting to membrane
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005784	Sec61 translocon complex
GO:0030176	integral component of endoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

InterPro

IPR009779 Translocon-associated, gamma subunit

PFAM

PF07074

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9UNL2

PhosphoSite

PhosphoSite-Q9UNL2

TrEMBL

C9J365

UniProt Splice Variant

Entrez Gene

6747

UniGene

Hs.711838

RefSeq

NP_009038

HUGO

HGNC:11325

OMIM

606213

CCDS

CCDS3176

HPRD

16206

IMGT

EMBL

AC092927 AF087907 AF110647 AK312935 BC017203 BT006669 CH471052

GenPept

AAD48587 AAH17203 AAP35315 AAP97205 BAG35777 EAW78730 EAW78731