Version 5.4
Mus musculus Protein: H2-Ke2
Summary
InnateDB Protein IDBP-626762.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2-Ke2
Protein Name H2-K region expressed gene 2
Synonyms H-2Ke2; H2-Ke2; Ke-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000133656
InnateDB Gene IDBG-168440 (H2-Ke2)
Protein Structure
UniProt Annotation
Function Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051082 unfolded protein binding
GO:0051087 chaperone binding
Biological Process
GO:0006457 protein folding
GO:0051131 chaperone-mediated protein complex assembly
Cellular Component
GO:0005634 nucleus
GO:0016272 prefoldin complex
Protein Structure and Domains
PDB ID MGI:95908
InterPro IPR002777 Prefoldin beta-like
IPR009053 Prefoldin
PFAM PF01920
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q03958
PhosphoSite PhosphoSite-Q03958
TrEMBL Q792E4
UniProt Splice Variant
Entrez Gene 14976
UniGene
RefSeq
MGI ID
MGI Symbol Pfdn6
OMIM
CCDS CCDS28636
HPRD
IMGT
EMBL AF100956 AF110520 AK010679 AK076015 AK167900 BC022974 CH466660 CR974462 M65255 M65256
GenPept AAA39368 AAA39369 AAC69895 AAC97975 AAH22974 BAB27111 BAC36121 BAE39911 EDL10228

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca