Version 5.4
Mus musculus Protein: Nfasc
Summary
InnateDB Protein IDBP-627002.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nfasc
Protein Name neurofascin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000132979
InnateDB Gene IDBG-192274 (Nfasc)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0086080 protein binding involved in heterotypic cell-cell adhesion
Biological Process
GO:0002175 protein localization to paranode region of axon
GO:0007411 axon guidance
GO:0007422 peripheral nervous system development
GO:0019226 transmission of nerve impulse
GO:0030913 paranodal junction assembly
GO:0034113 heterotypic cell-cell adhesion
GO:0045162 clustering of voltage-gated sodium channels
GO:0050808 synapse organization
GO:0071205 protein localization to juxtaparanode region of axon
Cellular Component
GO:0005886 plasma membrane
GO:0030424 axon
GO:0033010 paranodal junction
GO:0033270 paranode region of axon
Protein Structure and Domains
PDB ID MGI:104753
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
PFAM PF00041
PF01108
PF07679
PF07686
PF00047
PRINTS
PIRSF
SMART SM00408
SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-NP_001153788
TrEMBL E9PW06
UniProt Splice Variant
Entrez Gene 269116
UniGene Mm.326702
RefSeq NP_001153789
MGI ID
MGI Symbol Nfasc
OMIM
CCDS CCDS48359
HPRD
IMGT
EMBL AC116691 AC124095 AC159974
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca