Version 5.4
Mus musculus Protein: Man2a1
Summary
InnateDB Protein IDBP-627071.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Man2a1
Protein Name mannosidase 2, alpha 1
Synonyms Mana-2; Mana2; Map-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000130529
InnateDB Gene IDBG-194788 (Man2a1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0015923 mannosidase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0030246 carbohydrate binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0005975 carbohydrate metabolic process
GO:0006013 mannose metabolic process
GO:0006491 N-glycan processing
GO:0007005 mitochondrion organization
GO:0007033 vacuole organization
GO:0007585 respiratory gaseous exchange
GO:0048286 lung alveolus development
GO:0050769 positive regulation of neurogenesis
GO:0060042 retina morphogenesis in camera-type eye
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
Protein Structure and Domains
PDB ID MGI:104669
InterPro IPR011013 Galactose mutarotase-like domain
IPR011682 Glycosyl hydrolase family 38, C-terminal
PFAM PF07748
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6QMB7
UniProt Splice Variant
Entrez Gene 17158
UniGene Mm.2433
RefSeq
MGI ID
MGI Symbol Man2a1
OMIM
CCDS
HPRD
IMGT
EMBL AC154560 AC154577
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca