InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lig3

Summary

InnateDB Protein

IDBP-627087.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lig3

Protein Name

ligase III, DNA, ATP-dependent

Synonyms

D11Wsu78e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000133348

InnateDB Gene

IDBG-204684 (Lig3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003910	DNA ligase (ATP) activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006266	DNA ligation
GO:0006273	lagging strand elongation
GO:0006281	DNA repair
GO:0006288	base-excision repair, DNA ligation
GO:0006289	nucleotide-excision repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0006310	DNA recombination
GO:0043504	mitochondrial DNA repair
GO:0045910	negative regulation of DNA recombination

Cellular Component

GO:0000794	condensed nuclear chromosome
GO:0000795	synaptonemal complex
GO:0005634	nucleus
GO:0005694	chromosome

Protein Structure and Domains

PDB ID

MGI:109152

InterPro

IPR001510 Zinc finger, PARP-type
IPR012308 DNA ligase, ATP-dependent, N-terminal

PFAM

PF00645
PF04675

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3TJN5

UniProt Splice Variant

Entrez Gene

16882

UniGene

Mm.413071

RefSeq

MGI ID

MGI Symbol

Lig3

OMIM

CCDS

HPRD

IMGT

EMBL

AK167363 AL645594

GenPept

BAE39460