Version 5.4
Mus musculus Protein: Pcbp3
Summary
InnateDB Protein IDBP-627397.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcbp3
Protein Name poly(rC) binding protein 3
Synonyms AlphaCP-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000129465
InnateDB Gene IDBG-166344 (Pcbp3)
Protein Structure
UniProt Annotation
Function Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed, with highest levels in testis and fat tissues and lowest in heart. {ECO:0000269PubMed:10936052}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003723 RNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID MGI:1890470
InterPro IPR004044 K Homology domain, type 2
IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
PFAM PF07650
PF00013
PF13014
PRINTS
PIRSF
SMART SM00322
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P57722
PhosphoSite PhosphoSite-P57722
TrEMBL
UniProt Splice Variant
Entrez Gene 59093
UniGene Mm.486822
RefSeq XP_006513979
MGI ID
MGI Symbol Pcbp3
OMIM
CCDS CCDS35946
HPRD
IMGT
EMBL AF176327 AK034811 AK079564
GenPept AAG09238 BAC28838 BAC37686

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca