InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Klrk1

Summary

InnateDB Protein

IDBP-627474.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Klrk1

Protein Name

killer cell lectin-like receptor subfamily K, member 1

Synonyms

D6H12S2489E; NKG2-D; Nkg2d;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000130398

InnateDB Gene

IDBG-192142 (Klrk1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	6 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030246	carbohydrate binding
GO:0032394	MHC class Ib receptor activity
GO:0042288	MHC class I protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0002223	stimulatory C-type lectin receptor signaling pathway
GO:0030101	natural killer cell activation
GO:0032729	positive regulation of interferon-gamma production
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
GO:0050830	defense response to Gram-positive bacterium
GO:0071222	cellular response to lipopolysaccharide